Visualizations of vaccine-induced immune thrombotic thrombocytopenia (VITT)

Overview of VITT

This image was originally created to explain how some COVID-19 vaccines can, in very rare cases, cause blood clots. It was later adapted into a figure by S. Bradbrook/Springer Nature Limited for publication in Nature Reviews Immunology.

Citation: Kelton, J.G., Arnold, D.M. & Nazy, I. Lessons from vaccine-induced immune thrombotic thrombocytopenia. Nat Rev Immunol 21, 753–755 (2021). https://doi.org/10.1038/s41577-021-00642-8

Proposed mechanism for VITT antibodies forming platelet-activating immune complexes

Citation: Huynh, A., Kelton, J.G., Arnold, D.M. et al. Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia. Nature 596, 565–569 (2021). https://doi.org/10.1038/s41586-021-03744-4

Visualizations of vaccine-induced immune thrombotic thrombocytopenia (VITT)

Overview of VITT

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Citation: Kelton, J.G., Arnold, D.M. & Nazy, I. Lessons from vaccine-induced immune thrombotic thrombocytopenia. Nat Rev Immunol 21, 753–755 (2021). https://doi.org/10.1038/s41577-021-00642-8

Proposed mechanism for VITT antibodies forming platelet-activating immune complexes​

Citation: Huynh, A., Kelton, J.G., Arnold, D.M. et al. Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia. Nature 596, 565–569 (2021). https://doi.org/10.1038/s41586-021-03744-4

Proposed mechanism for VITT antibodies forming platelet-activating immune complexes